About CJC-1295 DAC
Growth hormones are some of the most popular supplements used by people worldwide. These supplements’ functionality and research compounds range from hair growth to muscle growth and even hormone production. The CJC-1295 is an analog GHRH (growth hormone releasing hormone), which increases IGF-1 (insulin-like growth factor 1) and plasma levels of growth hormone. It’s a synthetic research compound that extends the plasma half-life of CJC-1295.
What is CJC-1295 DAC
The GHRH has undergone various modifications to produce various analog versions of the growth hormone-releasing hormone, which exhibit the best properties of the hormone while eliminating some properties. The CJC-1295 DAC is one of the modifications of GHRH and contains only 29 amino acids from the parent molecule. It was developed to curate a soluble GH secretagogue and is categorized as an hGRF (1- 29) peptide, a maleimide derivative. It can be produced in large quantities while retaining the GHRH’s physiologic actions.
Even though CJC-1295 DAC and CJC-1295 are both modifications from the growth hormone-releasing hormone, the two aren’t identical. The two peptides have remarkable similarities because the CJC-1295 was created by adding the DAC (drug affinity complex) compound. The CJC-1295 peptide that contains the drug affinity complex compound is called CJC-1295 DAC, while the one that doesn’t contain the compound is called CJC-1295-no DAC or CJC-1295.CJC-1295 DAC is similar to the modified GRH (1-29) peptide.
CJC-1295 DAC Chemical Structure
- Sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-Lys-DAC
- Molecular Formula: C152H252N44O42
- Molecular Weight: 3647.954 g/mol
The CJC-1295 DAC chemical structure is different from the CJC-1295 chemical structure, which is:
- Sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg
- Molecular Formula: C152H252N44O42
- Molecular Weight: 3367.954 g/mol
CJC-1295 DAC Research
The CJC-1295 DAC has undergone various research studies, like other analog versions of the growth hormone-releasing hormone.
Growth Hormone Release
Since CJC-1295 DAC is derived from GHRH, it increases the level of GH in the body. When administered to mice, the peptide compound enhanced the GH levels in the mice by two to 10 times. The test mice experienced peak GH levels two hours after being administered the compound and high levels for six days after administration. The compound also prevented the physiological release of GH, hence retaining the typical circadian valleys and peaks in GH. CJC-1295 preserves the physiological release of GH while influencing the optimum concentration of the growth hormone in the bloodstream. Thus ensuring there are maximum effects from the peptide compound and reduced side effects. The compound has been demonstrated to preserve the following physiological effects of the GH on:
- Blood sugar
- Fat metabolism
- Bone density
- Heart cell function (myocardial)
- Protein synthesis
Studies involving mice that lacked the normal GHRH physiology revealed that CJC-1295 preserved the normal release of the growth hormone. Thus the peptide compound can be used as a treatment therapy for abnormal growth in various mammalian species. Preservation of the growth hormone’s standard pulsatile release ensures the efficient release of downstream hormones like the insulin-like growth factor-2 (IGF-1).
Research studies in the early 1990s suggested that GRF analogs and CJC-1295 could be instrumental in enhancing ovulation in female patients dealing with infertility. Many research studies have confirmed that ovulation depends on IGF-1 and is greatly influenced by GH release and cycle. Further research studies focusing on animal models of superovulation confirmed that animals’ GH and IGF-1 levels substantially increased during ovulation. The studies also confirmed that injection of GH secretagogues, e.g., CJC-1295, can cause appropriate ovulation. Some scientists and researchers have speculated that some analog versions of GH can be used in dealing with male infertility by regulating sperm production.
CJC-1295 DAC has excellent potential as a growth hormone secretagogue, with the ability to preserve the GH’s physiologic patterns and have an extended plasma half-life. The molecule has proven to be very successful on both occasions. However, the molecule has experienced limited research studies and interest due to the high number of similar molecules and the proprietary nature of the molecule. Since the production of synthetic CJC-1295, there is hope that researchers will now have an increased interest in the compound. When administered, the CJC-1295 exhibited limited side effects, impressive subcutaneous bioavailability, and low oral. Currently, the molecule is only limited to research and education purposes and is not available for human consumption.
CJC-1295 can potentially eliminate one of the most challenging issues in the world: human infertility. If you are a licensed researcher, you can purchase the molecule and research more on it.