Description
Physical Appearance: Fine white lyophilized powder
Contents: 1 mg GDF-8 (Propeptide-Fc) per vial
Peptide Purity: >99%
Solubility: 100 µg/mL in bacteriostatic water (for research use only)
Stability:
- Lyophilized: Store at -20°C
- Reconstituted: Store at 4°C and avoid repeated freeze-thaw cycles
Chemical Profile
Formula: Recombinant human myostatin propeptide fused with IgG Fc domain
Molecular Weight: ~80–100 kDa (dimeric fusion protein)
Purity: >99%
Peptide Class: GDF-8/myostatin inhibitor
Half-Life: ~3–5 days (due to Fc-fusion protein stability in vivo)
About GDF-8
GDF-8 (Propeptide-Fc) is a recombinant fusion protein consisting of the myostatin propeptide (the natural antagonist of GDF-8) linked to the Fc domain of human IgG, which extends its half-life and increases systemic stability. This compound has been studied for its ability to bind active myostatin, block signaling at the ActRIIB receptor, and thereby promote muscle growth and regeneration. It is a potent tool in myostatin inhibition research, with potential applications in muscle-wasting disorders, regenerative therapy, and metabolic disease models.
Research Studies
▪ Myostatin Inhibition
▪ Muscle-Wasting & Degeneration Models
▪ Extended Circulation Time
Disclaimer
GDF-8 (Propeptide-Fc) is sold strictly for laboratory research use. It is not approved for human or veterinary use, and must only be handled by licensed professionals in a controlled research environment.
