THIS PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should on be handled by licensed, qualified professionals.

SKU: GW-501516 Categories: ,


Concentration 30 mg per mL
Size 900 mg / 30 mL
Stability Room Temperature
Physical Appearance Clear Liquid
Molecular Formula C21H18F3NO3S2
LC-MS & HPLC 99% Purity

About GW-501516

The GW-501516 is commonly referred to as Cardarine GW 501516 and is a popular PPARδ receptor agonist. The receptors influence various functions of the body. During the research, scientists observed that Cardarine GW 501516 binds to the receptors and activates the AMP-activated protein kinase. The AMP-activated protein kinase focuses on providing the body with ample energy and securing the body’s survival capability during metabolic processes. When Cardarine GW 501516 activates this protein, it causes increased overall energy output and fat loss. It falls in the SARM category and isn’t regulated by the FDA or WDA.

What is Cardarine GW 501516?

Cardarine GW 501516 is a peroxisome proliferator-activated receptor delta and is one of three specific receptors of the PPAR group. It’s also a ligand-activated transcription factor. Apart from facilitating efficient and optimal metabolism processes, it also helps ensure the body has increased energy levels. Like most research compounds in the market, the Cardarine GW 501516 has various names, including GW1516, Endurobol, and GSK-516. Due to its ability to enhance the fat-burning process by the body, the research compound has shown the potential to prevent obesity among users.

Chemical Structure of Cardarine GW 501516

  • CAS: 317318-70-0
  • Molecular Formula: C21H18F3NO3S2
  • Molecular Weight: 453.498 g/mol


The Cardarine GW 501516 is very straightforward. The recommended Cardarine GW 501516 cycle should last a maximum of eight weeks. During the cycle, the dosage will only change once and remain constant until the cycle ends. In the first week, the recommended dosage is 10mg, giving your body enough time and quantity to get used to the Cardarine GW 501516 compound. You can increase the dosage in the send week to 20mg daily. Unlike the other research compounds like RAD 140 and Ostarine, you aren’t required to complete the PCT, but you still need to give your body ample recovery time after the cycle.

Research Studies on Cardarine GW 501516

The Brain

Several research studies have been done to determine the potentiality of Cardarine GW 501516 in improving the health and functionality of the brain. Even though the study wasn’t done on living things but brain cells, the findings were very impressive. The cluster of brain cells was prepared using an embryonal rat brain, and the researchers observed the inflammatory responses initiated by lipopolysaccharide (LPS) and IFN-gamma (interferon gamma). The IFN-gamma is a type II interferon class member and a dimerized soluble cytokine; it combines with molecules to create a dimer.

A dimer is a molecule that constitutes two identical molecules chemically linked together. On the other hand, the lipopolysaccharide (LPS) consists of polysaccharides and lipids, is bigger in size, and is located on the gram-negative bacteria’s outer membrane. The study focused on the reaction of lipopolysaccharide and IFN-gamma when the Cardarine GW 501516 compound is introduced into the system. Findings from the study showed that the Cardarine GW 501516 decreased the IFN-gamma-induced up-regulation of the iNOS and TNF-alpha. It also causes anti-inflammatory effects.

Cardiovascular Health

During a 12-week study, subjects were administered Cardarine GW 501516 in different doses: 10mg, 5mg, and 2mg. The patients who received the doses were healthy participants with high-density lipoprotein levels of less than 1.16mmol/L or an HDL. The researchers implemented different levels to ensure the study had a uniform baseline for all the participants. The implemented levels included: Fasting insulin, glucose, free fatty acid levels, and lipids. At the end of the study, the participants experienced a significant change in their cholesterol levels (HDL and LDL), concluding the Cardarine GW 501516 can be a reliable cardiovascular protection compound.

Weight Loss and Obesity

Two critical studies have been done to determine the effect of Cardarine GW 501516 in dealing with obesity by triggering weight loss. In the first study at the University of Maryland, six rhesus monkeys were placed on a specific diet comprising 13% fat, 69% carbohydrates, and 18% protein. Additionally, the scientists gave the monkeys a daily dosage of the Cardarine GW 501516 (0.1mg/kg), and at the end of the study, the dosage was increased to 3.0mg/kg daily. Findings from the study showed that the monkeys experienced reduced food consumption when they were given a “treat” twice every day, which contained the Cardarine GW 501516 compound. The second study involved mice placed on a high-fat special diet (35% fat content). After two months, the mice gained body weight by 30%, reduced body fat, and enjoyed increased glucose tolerance.

The Cardarine GW 501516 is one of a kind SARM with tremendous health potential. Even though the FDA or WADA hasn’t approved it, you can still use it. Thanks to its ability to improve recovery time and increase energy levels, it is branded the endurance SARM. It can also lower LDL cholesterol while increasing the growth of lean muscle mass. You can order the Cardarine GW 501516 and start enjoying the above health benefits; taking necessary precautions during your cycle will ensure you get the best results from the compound. Research studies are still ongoing to investigate any additional health benefits you can find from using the Cardarine GW 501516 compound. 

If you are ready to start your Cardarine GW 501516 journey, consider purchasing the SARM from high-quality dealers.

Additional information

Weight 0.15625 kg