THIS PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should on be handled by licensed, qualified professionals.

SKU: S-4 Category:


Concentration 50 mg per mL
Size 1,500 mg / 30 mL
Stability Room Temperature
Physical Appearance Clear Liquid
Molecular Formula C19H18F3N3O6
LC-MS & HPLC 99% Purity

About S-4

S-4 is a popular selective androgen receptor modulator (SARM) readily available in the market. According to various scientific studies, the SARM compound can treat benign prostatic hypertrophy, muscle wasting, and osteoporosis. It has gained immense popularity among users looking to retain lean muscle mass due to its potency and high oral bioavailability. However, like most SARM compounds, S-4 is only available for research purposes and is classified as a research compound. Even though it’s not FDA-approved, some individuals use it and have claimed to experience tremendous benefits in their cycles.

What is S-4?

S-4 is also known as Andarine S-4, a partial agonist of the body’s androgen receptors. According to research studies, the primary component of the compound is antiandrogen bicalutamide. Like other SARM compounds, the Andarine S-4 compound attaches itself to androgen receptors, proteins found in the body. It then causes the body to trigger bone and muscle growth that other factors like a chronic illness could have inhibited.

Andarine S-4 can only be ingested orally and has impressive oral bioavailability. Thus it hasn’t been associated with any effects on the liver or cardiovascular health. Various ongoing studies are looking at the possibility of using Andarine S-4 as a treatment option for osteoporosis, muscle wasting, and hypertrophy. Unlike anabolic steroids, Andarine S-4 only binds to specific receptors in the body, causing zero effects on other body organs. Its primary focus is the bones and muscle tissues.

Other essential health conditions which researchers believe could be treated with Andarine S-4 include:

  • Age-related muscle waste or loss (sarcopenia).
  • Prostate cancer
  • Enhance athletic performance
  • Involuntary weight loss for patients suffering from terminal illnesses (cachexia and wasting syndrome).
  • Enlarged prostate (BPH or benign prostatic hyperplasia)

Chemical Structure of the SARM Andarine S-4

  • Application: Partial agonist of androgen receptors
  • CAS:   401900-40-1
  • Molecular Weight: 441.363 g/mol
  • Chemical Formula: C19H18F3N3O6
  • Chemical Name: (2S)-3-(4-acetamidophenoxy)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl) phenyl] propanamide
  • Synonyms: Andarine, 401900-40-1, GTX-007, Andarine (GTX-007), UNII-7UT2HAH49H, Acetamidoxolutamide, Androxolutamide


Effects of Andarine S-4

Ongoing research studies focus on the possible health benefits of Andarine S-4. So far, there has been scientific confirmation and belief that the SARM compound can be a viable product in the treatment of muscle wasting conditions due to its lean muscle growth-triggering capabilities. Andarine S-4 binds with the androgen receptors to facilitate rapid muscle growth and retains lean muscle mass over an extended period. When combined with a high-protein diet and consistent workouts, patients with muscle wasting health conditions can easily attain their muscle-building goals.

Most individuals looking to gain lean muscle mass and lose body fat resort to using anabolic steroids, which have significant side effects. Andarine S-4 achieves the same result of lean muscle mass growth without causing side effects linked to anabolic steroids. During the research studies involving the use of Andarine S-4, scientists made the following key observations:

At the end of the cycle, subjects didn’t exhibit any breast lactation or female characteristics.

  • The compound has a very low cardiovascular risk since it doesn’t trigger the increase of high-density lipoprotein (HDL) and low-density lipoprotein (LDL) cholesterol.
  • It doesn’t affect the natural levels of testosterone in the body.
  • The subjects didn’t develop any liver toxicity.
  • Female test subjects who used the compound didn’t exhibit masculine features.

Apart from the above observations, which confirm the safety levels of Andarine S-4, the compound doesn’t affect the vital organs in the body.

Proper Dosage of Andarine S-4

Several key factors determine the correct dosage of Andarine S-4. The most important ones are the user’s fitness goals, health, and age. No scientific evidence supports the appropriate dosage for the SARM compound. Most of the research studies have been done on animals, and Researchers can’t use the dosage used on animals on humans. Nevertheless, when purchasing the Andarine S-4 SARM compound, the manufacturer will give the recommended dosage you are supported to follow. Don’t be a victim of believing that higher doses mean faster and more profound results. You can confirm the most appropriate dosage with your doctor or pharmacist.

 Negative Effects of Andarine S-4

When you take any foreign compounds, you interfere with the body’s metabolism. The same case applies when one takes any selective androgen receptor modulator, including Andarine S-4. So far, researchers have reported minimal information regarding possible side effects of the Andarine S-4 SARM compound. However, one profound observation was the presence of a yellow tint in the test subject’s vision. Some test subjects found it hard to adjust to dim light. Researchers also observed that the Andarine S-4 compound became less effective with time hence the need to increase the dosages as the cycle continued. Most side effects associated with selective androgen receptor modulators are dose-dependent; hence sticking to the correct doses will reduce the chances of one experiencing any side effects. If one experiences any side effects, they should stop using the SARM compound and consult with a doctor, or preferably reduce their daily dosage.

Andarine S-4 might be a new SARM compound in the industry, but there is plenty of hope that doctors can use it in treating muscle wasting health conditions and osteoporosis. Like other selective androgen receptor modulators, the compound selectively binds itself to the androgen receptors in the body. Even though it falls in the category of research chemicals, when used appropriately, the compound can cause impressive lean muscle mass growth and muscle retention in the body. Users can also stack it with other SARM compounds to achieve their bulking or shredding goals. The uncertainty and lack of information regarding the side effects caused by the Andarine S-4 compound might be a significant setback in using the compound, especially among athletes. The other demerit is its decreasing effect as one progresses with the Andarine S-4 cycle, requiring the dosage to be increased. Conclusively it’s best to wait for more scientific evidence and information regarding the proper dosage and possible side effects of the Andarine S-4 compound. 

Andarine S-4 selectively binds to the androgen receptors to facilitate lean muscle growth. Despite promising results, there is very little scientific evidence and information regarding the compound’s dosage and possible side effects.

Additional information

Weight 0.15625 kg